Metal Gear Solid 4: Guns of the Patriots is a video game developed by Kojima Productions for the PlayStation 3. The game was directed by Hideo Kojima and made its worldwide release on June 12, 2008, ten years after the release of Metal Gear Solid and twenty years after the North American release of Metal Gear.

Metal Gear Solid 4 is set in 2014, nine years after the plot of Metal Gear Solid and five years after Metal Gear Solid 2: Sons of Liberty. The world economy relies on continuous war, fought by PMCs, which outnumber government military forces. PMC soldiers are outfitted with nanomachines that enhance their abilities on the battlefield. The control network created through these nanomachines is called Sons of the Patriots (SOP), and Liquid Ocelot is preparing to hijack the system. Snake, meanwhile, is experiencing accelerated aging due to his status as a clone, and has less than a year to live. When his former commanding officer Roy Campbell approaches him with one last mission - to terminate Liquid - Snake accepts and is dropped into the Middle Eastern war zone where Liquid is believed to be hiding.

Guns of the Patriots received widespread critical acclaim, garnering perfect reviews and Game of the Year awards from several major gaming publications, including GameSpot, which said that the game is "technically flawless". The game has been a financial driving force for Konami, helping the Metal Gear franchise reach 5 million units in the financial year of 2009.